Not sure we'll see mass changes, but I would make the following:
Paix out - Billy to start at 9
Hunt out - Mozer to stay on bench
Shibasaki out - Mariner to centre, Karapani back to wing. If you can't bring him back due to his latest shit-4-brains episode then go with Arthars (unless Perham can play wing)
I think you would also need to consider bringing Mam back in. Duffy is a talented halfback, but I'm not sure he's working at 6. His running game seems to have been non existent in the 6...