Probably a bit kneejerk, but this is the XI I'd be picking myself for South Africa.
1. David Warner
2. Will Pucovski
3. Marnus Labuschagne
4. Steve Smith (c)
5. Glenn Maxwell (vc)
6. Cameron Green
7. Ben McDermott (wk)
8. Pat Cummins
9. Jhye Richardson
10. Josh Hazlewood
11. Mitch Swepson
Think Paine, Wade, Starc & Lyon all need to go.
It's a tough call between McDermott, Inglis & Philippe to replace Paine.. Philippe clearly has the highest potential of the 3, but based on records in Shield as well as current form (Coming off a 100 not out for Australia A), I think McDermott deserves first crack.
Maxwell is pure talent, brings high energy in the field and a wealth of experience in a variety of conditions and formats. Happy to throw him straight in.
Richardson is a no-brainer, he's the form fast bowler in Australia besides Cummins. Dominating every single arena he's thrown in to. Just needs to stay fit.
Swepson is next in line for Australia, has been for a while. Plenty of wickets in Shield, continuing to improve every season, deserves a chance.